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WELCOME TO COMIC TRIAL

Cuff Leak and Airway Obstruction in Mechanically Ventilated ICU Patients: A Randomized Controlled Trial

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WHAT IS COMIC TRIAL?

COMIC Trial is a pragmatic randomized clinical trial that aims to examine the efficacy and safety of performing cuff leak test prior to extubating mechanically ventilated critically ill patients.

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RESEARCH PROGRAM

COMIC Survey

COMIC Survey is a international project that aims to determine the variability in practices and believes of critical care physicians and respiratory therapists with regards to the diagnostic and clinical utility of cuff leak test in the intensive care unit (ICU). We will use MetaClinician software to administer the survey to participants.

COMIC Pilot Trial

COMIC Pilot Trial is a pragmatic randomized clinical trial, the goals of which are to determine the feasibility and acceptability of doing a large trial that will examine the clinical and diagnostic utility of cuff leak test in the ICU.

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Quantitative Cuff Leak Measurement

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